Synthesis of spiro[pyrazole-4,8′-pyrazolo [3,4-f]quinolin]-5(1H)-ones by the reaction of aldehydes with 1H-indazol-6-amine and 1H-pyrazol-5(4H)-one

[摘要] A four-component reaction including two equivalents of aldehyde, 1 H -indazol-6-amine and 1 H -pyrazol-5(4 H )-one proceeds smoothly to afford a series of spiro[pyrazole-4,8′-pyrazolo[3,4- f ]quinolin]-5(1 H )-ones in high yields under catalyst-free conditions.

[学科分类] 内科医学

[关键词] 1H-indazol-6-amine;1H-pyrazol-5(4H)-one;pyrazoloquinoline;spiro