Synthesis and fungicidal activities of 2-{[(2-(1H-1,2,4-triazol-1-yl)-ethylidene)amino]oxy}alkanamides containing dihydrobenzofuran

[摘要] In order to find new compounds with high fungicidal activity, acetamide derivatives 4a–x were rationally designed, synthesized, characterized and tested against various fungi in vivo . The bioassay results indicate that compounds 4k,m,o,r exhibit an 80% inhibition rate against Rhizoctonia solani at 500 mg/L, and compound 4j shows an 80% inhibition rate against Blumeria graminis at 500 mg/L. Therefore, compounds of 4 are promising fungicidal candidates worthy of further development.

[学科分类] 内科医学

[关键词] amides;dihydrobenzofuran;fungicidal activity;synthesis