Efficacy and economic impact evaluation of a navigation system for assisted lung biopsy

[摘要] This Letter reports on the testing and assessment of an optical computed tomography-navigation system for percutaneous lung interventional, SIRIO, showing how the lesion diameter affects the bioptic procedure. Clinical data, relating to 501 patients, were collected at the Department of Interventional Radiology of Policlinico Universitario Campus Bio-Medico. This Letter shows that the diameter of lesion affects only the procedure duration (50.91 ± 18.87 min for lesions of diameter ≤20 mm and 44.98 ± 19.43 min for lesions of diameter >20 and ≤40 mm). For the nodules with a diameter ≤20 mm, there is a significant increase in the duration of the procedure (for each mm less the time increases by 6 s). Other parameters like the mean effective radiation dose and the presence of a diagnostic or non-diagnostic specimen do not depend, instead, on the lesion size. The economic analysis based on the biopsy procedure with SIRIO shows the necessity to adopt a new reimbursement system for percutaneous biopsy performed using navigation systems to stimulate their use to get important non-economic gains such as early diagnosis, reduction of the absorbed dose of X-rays and increasing number of lung cancers in a curable early stage.

[学科分类] 肠胃与肝脏病学

[关键词] lung;cancer;optical tomography;dosimetry;computerised tomography;biomedical optical imaging;economics;efficacy;economic impact evaluation;navigation system;assisted lung biopsy;optical computed tomography-navigation system;percutaneous lung interventional;SIRIO;lesion diameter;bioptic procedure;Department of Interventional Radiology;Policlinico Universitario Campus Bio-Medico;mean effective radiation dose;lesion size;percutaneous biopsy;noneconomic gains;early diagnosis;absorbed dose reduction;lung cancers