Evaluation of the effect of piezo-intracytoplasmic sperm injection on the laboratory, clinical, and neonatal outcomes

[摘要] Purpose: Limited research has been published on the effect of piezo-assisted intracytoplasmic sperm injection (P-ICSI). We evaluated the effect of P-ICSI on the laboratory, clinical, and neonatal outcomes. Methods: This retrospective study was based on the data collected between April 2011 and October 2016. Total 1348 mature oocytes from 145 patients were analyzed. Laboratory, clinical, and neonatal outcomes of those given conventional intracytoplasmic sperm injection (C-ICSI) and those administered P-ICSI were examined. Results: P-ICSI showed significantly more favorable results, with a survival rate of 97.0% (C-ICSI: 94.1%, P < .010) and a fertilization rate of 83.5% (C-ICSI: 70.6%, P < .001). There were no differences in the blastocyst development rate, implantation rate, miscarriage rate, live birth rate, gestational age, birth weight, proportion of male neonates, cesarean section rate, and congenital abnormalities between the two patient groups. Conclusions: Our comparison of P-ICSI with C-ICSI showed that P-ICSI significantly improved the survival and fertilization.

[学科分类] 工业工程学

[关键词] assisted reproductive technology;fertilization;ICSI;neonatal outcomes;piezo