Metabolism of exogenous fatty acids, fatty acid-mediated cholesterol efflux, PKA and PKC pathways in boar sperm acrosome reaction

[摘要] Background : Aquatic program is an occupational therapy for children with neurodevelopment disorder that has been recognized as one of the technological innovations in medical rehabilitation. This study aimed to analyze the effectiveness of occupational therapist empowerment training in aquatic program on the knowledge, attitude, and competence of occupational therapists, and the effectiveness aquatic therapy on improving the development of children with neurodevelopment disorder. Subje cts and Method : This was a quasi experiment study with pre and post test design with no comparison design. A sample of 88 occupational therapist were selected for this experiment. Knowledge, attitude, and competence of the therapists before and after empowerment training were measured and compared. Likewise, 78 children with neurodevelopmental disorder in Central Java who were under treatment by the occupational therapists were measured and compared before and after the occupational therapist empowerment training, in terms of motoric and sensoric development. The effects of empowerment training on knowledge, attitude, and competence of the occupational therapists as well as motoric and sensoric development of children with neurodevelopment disorder were analyzed by linear regression analysis model. Results : Empowerment training significantly increased knowledge (b=3.95; 95% CI=  3.55 to 4.34; p<0.001), attitude (b=3.49; 95% CI=  2.84 to 4.14; p<0.001), and  competence (b=2.73; 95% CI= 1.93 to 3.53; p<0.001) of the occupational therapists. Aquatic therapy resulting from empowerment training significantly increased motoric (b=1.39; 95% CI= 1.04 to 1.74; p <0.001) and sensoric (b=2.79; 95% CI= 2.13 to 3.45; p<0.001) development of children with neurodevelopment disorder. Conclusion : Empowerment training effectively increases knowledge, attitude, and competence of occupational therapists. In turn, aquatic therapy conducted by the occupational therapists effectively increases motoric and sensoric development of children with neurodevelopment disorder.

[学科分类] 工业工程学

[关键词] Acrosome reaction Boar sperm Cholesterol efflux Incorporation and oxidation of fatty acid PKA and PKC