Cryopreservation in ART and concerns with contamination during cryobanking

[摘要] Background: Stroke risk factors disparities in race-ethnic. Bataknese is the most stroke rates compared to non-Bataknese at H. Adam Malik General Hospital Medan. This may be due to genetics and lifestyles that have a link to increase stroke risk factors in Bataknese. Bataknese has a characteristic lifestyle that is more eating, typical foods also contain lots of cholesterol, and have a habit of drinking traditional alcoholic beverages. Subjects and Method:  This was a cross-sectional study selected by consecutive sampling tech­niques, clinically proven stroke patients and computed tomography (CT) scan studied at H. Adam Malik General Hospital Medan from June to November 2018. This study aimed to know the difference of stroke risk factor between stroke patient of Bataknese and non-Bataknese. Results: This study recruited 70 samples consisting of 45 Bataknese and 25 non-Bataknese. There were no significant differences in risk factors for hypertension, dyslipidemia, heart disease, dia­betes mellitus, smoking, and obesity among stroke patients in the Bataknese and non-Bataknese. But the distribution of hypertension was higher in Bataknese (50%) compared non-Bataknese (30%) (PR=0.67, 95%CI= 0.19 to 2.40, p= o.755). Dislipidemia was higher in Bataknese (38.6%) compared non-Bataknese (18.6%) (PR=1.39, 95% CI= 0.52 to 3.71, p=0.692). Heart disease was higher in Bataknese (17.1%) compared non-Bataknese (8.6%) (PR=1.15, 95% CI= 0.37 to 3.57, p= 1.000).  Diabetes mellitus was higher in Bataknese (17.1%) compared non-Bataknese (10%) (PR=1.10, 95% CI= 0.31 to 2.87, p=1.000). Smoke was higher in Bataknese (27.1%) compared non-Bataknese (14.3%)(PR= 1.59, 95% CI= 0.38 to 6.61, p=1.000). Obesity was higher in Bataknese (11.4%) compared non-Bataknese (4.3%) (PR=1.59, 95% CI= 0.38 to 6.61, p=0.735). There was significant differences in risk factors for alcohol consumption between stroke patients in the Bataknese and non-Bataknese, where alcohol consumption was higher in the Bataknese (15.7%) compared non-Bataknese (1.4%) (PR=7.77, 95% CI= 0.94 to 64.22, p=0.045). Conclusion: A significant difference in stroke risk factors between stroke patients in Bataknese and non-Bataknese was alcoholic consumption.

[学科分类] 工业工程学

[关键词] Closed device Contamination Cryopreservation Liquid nitrogen Vitrification