Estimation of Beta Two Microglobulins, Fetuin-A, Resistin Serum Level in Iraqi Multiple Myeloma Patients

[摘要] Multiple myeloma is hematological disease produces many complications in the bone, kidney, neural and other complications. The study aims to measure serum biomolecules like fetuin-A and resistin and determined the possibility to use these biomarkers as disease predictor. blood samples were isolated from 58 patients and 24 sex and age-matched control, serum then isolated, and proper ELISA kit then used to a determined level of β2 microglobulin, resistin, and fetuin-A. The result demonstrated significant increase in β2 microglobulin, fetuinA and resistin in patients compare to control (1.347±0.714 vs. 0.913±0.253), p = 0.000, (14.003±10.352 vs. 9.259±4.264), p= 0.005, (1.967±3.595 vs. 0.604±0.622), p = 0.009, respectively. These differences give the possibility to use these biomolecules as a predictor in multiple myeloma.

[学科分类] 计算机网络和通讯

[关键词] Multiple myeloma;Fetuin-A;Resistin.