Histopatholgical changes in the mice model of surgical unilateral cryptorchidism

[摘要] This study was done on 20 male mice (35 – 45) days with weight of (18 – 20) grams divided into four groups, each group contains five animals.The first group regarded as control and remain intact. The second, third and fourth group were subjected to experimental unilateral cryptorchidism to render them cryptochild by putting the testes inside the abdominal cavity and suture the inguinal canal.Second group were killed after 10 days from the operation, the third group were killed after 20 days & fourth group were killed after 30 days.This study confirms that intraabdominal cryptorchid testes are impaired spermatogenesis due to abnormal localization, decrease in testicular volume in the cryptorchid group, seminiferoustubular atrophy, basnet membrane thickening, germ cell loss and spermatogenic arrest were more evident with time being highest at the 30 days.

[学科分类] 土木及结构工程学