Analgesic effect of the aqueous extract of Artimisia herba alba Arial part

[摘要] The present study was aimed to investigate the analgesic effects of the aqueous extract of Artimisia herba alba Arial part in rats and mice ( AEAHA ) . The AEAHA (400- 700 mg/kg; p.o.) was evaluated for its analgesic activity by employing acetic acid-induced writhing test, hot plate test and tail immersion tests i.e. in hot and cold water. AEAHA (400- 700 mg/kg; p.o.) showed significant (P<0.01) reduction in the number of writhing induced by acetic acid, increased reaction time in hot plate test and elevated pain threshold in hot and cold water tests. AEAHA exhibited the dose-dependent analgesic effects.

[学科分类] 土木及结构工程学

[关键词] Artimisia herba alba;Analgesic activity;Writhing;Hot plate;Tail immersion tests