TLRs toll for Tregs

[摘要] Food allergy (FA) is an immune mediated pathologic condition in response to normally innocuous food antigens with the prevalence increasing in both Western and fast-developing countries. Food allergens are derived from common food proteins of plant and animal origin. The adverse immune responses in FA consist of IgE-mediated immediate hypersensitivity reactions, non-IgE-mediated reactions, and conditions involving mixed IgE-mediated and cell-mediated immune reactions.1–3 The allergic responses are mediated by the participation of a range of innate and adaptive immune cells, such as mast cells, basophils, and eosinophils, type 2 innate lymphoid cells (ILC2s) as well as activated Th2 cells and B cells switched to the production of IgE.

[学科分类] 生理学