Current review of surgical management options for extremity bone sarcomas

[摘要] The dawn of extremity bone sarcoma management was dominated by amputation as a standard of surgical treatment. Although some attempts were made to perform limb-sparing procedures, by carrying out segmental resection and reconstruction using bone grafts or endoprostheses, the limiting factor for favourable and sustainable results was local tumour recurrence. Everything changed when chemotherapy (neoadjuvant or adjuvant) and radiation therapy were instituted in the treatment protocols for extremity sarcomas during the last quarter of the 20th century, driving down the risk for local recurrence after both ablative or limb-preserving procedures. Furthermore, the development of medical imaging and surgical techniques ensured more efficient, oncologic resections of sarcomas and, with that, limb-sparing procedures became the generally accepted standard of treatment.

[学科分类] 神经科学

[关键词] Bone sarcoma;reconstruction;modular endoprostheses