Cluster-tic syndrome as the initial manifestation of multiple sclerosis

[摘要] We report the case of a patient diagnosed as having cluster-tic syndrome as the initial manifestation of multiple sclerosis (MS). The patient’s headache bouts improved after treatment with antiepileptic drugs, steroids, and beta-interferon. Magnetic resonance imaging (MRI) scans showed a pontine demyelinating lesion involving the area of the trigeminal root inlet and main sensory nucleus. Neurophysiological studies correlated well with MRI lesions. The association between cluster-tic syndrome and MS is an exception, and the mechanism of the pain is still unknown; therefore, this case might suggest a pathophysiological relationship between the trigeminal main sensory nucleus and cluster-tic syndrome.

[发布日期] 2012-04-28

[关键词] Cluster Headache;Pregabaline;Magnetic Resonance Imaging Study;Trigeminal Neuralgia;Magnetic Resonance Imaging Lesion