Age is an important prognostic factor in COVID-19 patients treated with extracorporeal membrane oxygenation

[摘要] Coronavirus disease 2019 (COVID-19) is a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection affecting multiple organs and may progress to severe acute respiratory distress syndrome (ARDS). In South Korea, the shortage of intensive care unit (ICU) and application of extracorporeal membrane oxygenation (ECMO) are increasing due to the recent rapid increase in the number of critically ill patients with COVID-19. ECMO has been used in ARDS and reduces the 60-day mortality compared to that with conventional management (1). In the metaanalysis by Combes et al., 90-day mortality was significantly lower in the ECMO group than in the conventional management group [36% vs. 48%; relative risk 0.75; 95% confidence interval (CI): 0.6–0.94; P=0.013] (2). Mortalityrelated factors in ECMO include the age, malignancy, liver cirrhosis, ventilator setting [positive end-expiratory pressure (PEEP)], peak inspiratory pressure (PIP)], respiratory ECMO survival prediction (RESP) score, and predicting death due to severe ARDS on VV-ECMO (PRESERVE) score (3,4).

[学科分类] 呼吸医学