Liver transplantation for cholangiocarcinoma: exploring a new land

[摘要] CCA is a rare malignancy arisen from biliary system, whose incidence is increasing in these years. According to the tumor anatomical location with the second-order bile ducts, CCA is classified as intrahepatic CCA (iCCA) and extrahepatic CCA (eCCA). Surgical resection is a preferred management of cholangiocarcinoma, when radiofrequency ablation, transarterial chemoembolisation, and radiotherapy are optional treatments for those unresectable tumors (1). LTx is a considerable treatment with some liver diseases, especially early-stage hepatocellular carcinoma and is widely performed over the world, providing better prognosis. However, CCA is considered as contraindication of LTx for a long time until some studies reveal the potential management in selected patients.

[学科分类] 肿瘤学