Meta-analysis and systematic review of the relationship between ulcerative colitis and colon cancer

[摘要] We thank Guo et al. for their comments on our published article “Secondary colon cancer in patients with ulcerative colitis: a systematic review and meta-analysis” (1). After verification, the interpretation of P<0.00001 is significantly different, so it is concluded that there is a relationship between colon cancer and colitis (2). After consideration, in prospective studies, such as cohort studies and randomized controlled trial (RCT), not only relative risk (RR) but also odds ratio (OR) can be calculated (3). Generally, RR is used in many cohort studies and RCT when reporting the results. However, the overall rate of this study is low, so OR is similar to RR, and so it is correct to use OR.

[学科分类] 肿瘤学