Microenvironmental regulation of stem cells injected in the area at risk of neurodegenerative diseases

[摘要] The complex mechanism of degenerative diseases and the non-specific modulation of regenerative targets aretopics that need to be elucidated in order to advance the use of stem cells in improvement of neurodegenerative diseases.From pre-transplantation through post-transplantation, there are many changes in the conditions, both inside andoutside of the stem cells that have not been carefully considered. This has hindered development in the field of celltherapy and regeneration. This viewpoint highlights the potential implications of intracellular and extracellularalterations of stem cells in transplanted areas at risk of neurodegenerative disease.

[学科分类] 仪器

[关键词] Cell therapy;Microenvironment;Neurodegenerative disease;Stem cells