Apigenin as a promising myocyte protectant against damage and degradation

[摘要] Myocytes power the movement of all organs in the body. Damage to and degradation of myocytes causeshypokinesia and muscle-related degenerative diseases. Apigenin, a kind of flavone, is being used to treat manydisorders. It exerts a host of different pharmacological activities, such as anti-inflammatory, anti-mutagenic,cardioprotective, and antioxidant effects. Accordingly, apigenin is considered a promising candidate for myocyteprotection. In this review, we introduced the characteristics of apigenin. The means of apigenin protection ofmyocytes as well as the mechanism were summarized and discussed. The protective effects can be classified intoproliferation-promoting, anti-inflammatory, atrophy-preventing, metabolism-increasing, and antioxidative effects.Additionally, we provided some outlook on the valuable applications of apigenin in sports medicine, which eagerlyrequire further fundamental research.

[学科分类] 仪器

[关键词] Apigenin;Myocyte;Protectant;Pharmacological activity