Exocytosis, endocytosis and recycling of secretory vesicles in neuroendocrine cells, and its regulation by cortical actin

[摘要] The cortical actin network is a mesh of filaments distributed beneath the plasmalemma that dynamically reactsin response to stimuli. This dynamic network of cortical filaments, together with motor myosin partners, adjusts theplasmalemma tension, organizes membrane protein microdomains, remodels the cell surface and drives vesiclemotion in order to fine-tune exocytosis, endocytosis and recycling of secretory vesicles. In this review, we discuss howthese mechanisms work in secretory cells.

[学科分类] 仪器

[关键词] Cortical actin;Neuroendocrine cell;Chromaffin cell;Exocytosis;Endocytosis