New evidence for a role of Bisphenol A in cell integrity. Implications in the human population

[摘要] Bisphenol A (BPA) is a xenoestrogen known for its implications for the endocrine systems and several other organs, including the kidneys. Recent renal studies have shown that BPA can induce alterations of the cytoskeleton and cell adhesion mechanisms such as a podocytopathy with proteinuria and hypertension, alterations involved in the progression of renal diseases. These data and the fact that BPA is known to be present in the urine of almost the entire population strongly suggest the critical need to reevaluate BPA exposures considered safe.

[学科分类] 仪器

[关键词] Bisphenol A;Podocyte;Cytoskeleton;Cell Adhesion;Chronic Renal Diseases;Dialysis