Letter to the Editor concerning “An unexpected connection: a narrative review of the associations between gut microbiome and musculoskeletal pain” by Tonelli et al. (Eur Spine J; 2022: doi:10.1007/s00586-022–07429-y)

[摘要] We were intrigued by the article by Tonelli et al. [1], whichdiscussed a narrative review of the unforeseen associationbetween the gut microbiome and musculoskeletal pain.However, with recent advances in this area, we have someconcerns about this paper.First, since there has been a large amount of evidenceto support that the gut microbiota is associated with manyfactors that modulate the fracture risk [2], the author shouldemphasize the link between the gut microbiota and metabolic bone diseases, such as osteoporosis, when describingmusculoskeletal pain.

[学科分类] 骨科学