An unexpected connection: A narrative review of the associations between Gut Microbiome and Musculoskeletal Pain

[摘要] Purpose Multiple diverse factors contribute to musculoskeletal pain, a major cause of physical dysfunction and health-related costs worldwide. Rapidly growing evidence demonstrates that the gut microbiome has overarching influences on human health and the body’s homeostasis and resilience to internal and external perturbations. This broad role of the gut microbiome is potentially relevant and connected to musculoskeletal pain, though the literature on the topic is limited. Thus, the literature on the topic of musculoskeletal pain and gut microbiome was explored.

[学科分类] 骨科学

[关键词] Gut microbiome;Musculoskeletal pain;Inflammation;Homeostasis;Pain modulation