Device-based therapies for resistant hypertension in chronic kidney disease: The continuing quest for a cure

[摘要] Hypertension can be a cause or consequence of chronic kidney disease (CKD), in which sodium retention and volume expansion, increased activity of the renin-angiotensin system, and increased sympathetic nervous system activity can all contribute to raising blood pressure. Resistant hypertension, which is associated with a higher risk for adverse outcomes, is overrepresented in CKD. An analysis from the CRIC (Chronic Renal Insufficiency Cohort) study showed a high prevalence of apparent treatment-resistant hypertension in CKD (about 40%), with a 38% increase in risk for adverse cardiovascular events and 28% increase in risk for adverse renal events.1 This underscores the importance of blood pressure control in this population, and novel therapeutic strategies should be explored.

[学科分类] 卫生学