Our evolving understanding of primary aldosteronism

[摘要] Primary aldosteronism is the most common endocrine cause of hypertension, and is often associated with treatment-resistant hypertension.1 It is characterized by autonomous aldosterone production independent of renin activity, potassium level, or volume status. Its prevalence has been debated, and studies are fraught with limitations, including reliance on tests that do not confirm the diagnosis. It has been identified as a public health issue,2 and the urgency in identifying and treating it is heightened by its strong association with adverse kidney and cardiovascular outcomes.

[学科分类] 卫生学