SGLT-2 inhibitors: A new era in managing diabetic kidney disease starts now

[摘要] Diabetic kidney disease is a major cause of chronic kidney disease and the most common cause of end-stage kidney disease. Before the sodium-glucose cotransporter-2 (SGLT-2) inhibitors were introduced, the nephrology community had not had much to celebrate in the management of diabetic kidney disease since the landmark trials of renin-angiotensin system blockers 20 years ago.1–3 Since that time, angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers have been the cornerstone of managing proteinuric diabetic and nondiabetic kidney disease. Fast-forward 20 years, and SGLT-2 inhibitors have emerged as a major addition to our toolkit in the management of diabetic kidney disease.

[学科分类] 卫生学