Parkinson disease primer, part 1: diagnosis

[摘要] Objective To provide family physicians an updated approach to the diagnosisof Parkinson disease (PD).Sources of information Published guidelines on the diagnosis andmanagement of PD were reviewed. Database searches were conducted toretrieve relevant research articles published between 2011 and 2021. Evidencelevels ranged from I to III.Main message Diagnosis of PD is predominantly clinical. Family physiciansshould evaluate patients for specific features of parkinsonism, then determinewhether symptoms are attributable to PD. Levodopa trials can be used tohelp confirm the diagnosis and alleviate motor symptoms of PD. “Red flag”features and absence of response to levodopa may point to other causes ofparkinsonism and prompt more urgent referral.Conclusion Access to neurologists and specialized clinics varies, and Canadianfamily physicians can be important players in facilitating early and accuratediagnosis of PD. Applying an organized approach to diagnosis and consideringmotor and nonmotor symptoms can greatly benefit patients with PD. Part 2 inthis series will review management of PD.

[学科分类] 卫生学