Exploring Natural Medicine for the Suppression of Osteocyte Apoptosis

[摘要] An Osteonecrosis of the Femoral Head (ONFH) is a debilitating disease that results from the loss of blood supply to the bone tissue of thefemoral head. It is a progressive condition that can lead to the collapse of the femoral head, joint deformity, and ultimately, hip replacementsurgery. While the exact cause of ONFH is still unknown, it is believed that a variety of factors, including steroid use, alcohol consumption,and trauma, can contribute to its development. Current treatment options for ONFH include conservative management, such as painmanagement and activity modification, as well as surgical intervention. However, these treatments are often associated with a high rate offailure and can lead to significant morbidity and mortality. Therefore, there is a growing interest in developing new and more effectivetreatments for ONFH, including natural medicine.

[学科分类] 药理学