The significance of Pre and Post exposure prophylaxis in Disease Control and Prevention

[摘要] In the United States of America, Human Immunodeficiency Virus (HIV) is a major public health concern. Presently, an estimated 1.1million people are infected with HIV. Despite a 4.3% decrease in new HIV infections from 41,942 in 2012 to 40,534 in 2016, improvementhas been unequal among different groups and geographic places in the United States of America and six dependent countries. Almost 70%of new diagnoses in 2016 occurred among males who had sex with men, and they were disproportionately concentrated among minorities.The South had the largest proportion (51%) and rate (16.8 diagnoses per 100,000 people) of new HIV infections. Truvada, an antiviral drug,is widely used for Pre-Exposure Prophylaxis (PrEP) and is extremely successful in avoiding HIV infections. PrEP therapy comprises oftaking Tenofovir Disoproxil Fumarate (TDF) plus another drug, Emtricitabine (FTC), on a regular basis.

[学科分类] 药理学