The Impact of Acetaminophen in Blood Pressure Monitoring

[摘要] The most widely prescribed painkiller in the world, acetaminophen (also known as paracetamol) is one of the substitutes on the bottom rungof the WHO analgesic ladder for treating cancer pain. Acetaminophen's effectiveness as an analgesic for chronic pain has recently comeunder scrutiny. Nevertheless, clinicians and patients feel comforted about continued long-term use because acetaminophen is thought to besafe. This is still the case when compared to replacement over-the-counter analgesics such non-steroidal anti-inflammatory drugs, whichhave well-known adverse effects include increased cardiovascular risk, hypertension, gastrointestinal ulcers, and acute renal injury. The useof analgesics is highly widespread, just like pain. The implications of even a small increase in cardiovascular risk from commonlyprescribed analgesics can be profound; if the most widely used analgesic in the world were to significantly raise blood pressure, this wouldbe a catastrophe for global public health. Acetaminophen's safety profile is currently under evaluation. Previous observational studies havefound correlations with a rise in unfavorable gastrointestinal, renal and cardiovascular events.

[学科分类] 药理学