Mechanisms of Antibiotic Resistance Genes

[摘要] Antibiotic overuse and misuse have traditionally been blamed for the global development of Antibiotic Resistance Genes (ARGs), whichhave played havoc on the effectiveness of antibiotic treatment and eventually anti-microbial chemotherapy. However, due to the ancientARGs' altered roles in bacterial physiology, non-antibiotic factors may also affect how they are controlled. Numerous non-antibioticsubstances, including micro plastics, metallic nanoparticles, non-antibiotic medications, and non-antibiotic circumstances, as well as somenon-antibiotic situations, have been shown to hasten the spread of ARGs and the importance of antibiotics may have been overstated in thepast, while the impacts of non-antibiotic circumstances may have gone unnoticed.

[学科分类] 药理学