The New Phase in Bacteria-Based Drug Delivery Therapies using Nano Biomaterials

[摘要] Bacteria began to play a part as a new type of cancer treatment over a century ago. Researchers are currently focused on the potential linksbetween host-microbe interactions and human health/disease. In recent years, microbial treatment has been regarded as a therapeutictechnique for a variety of disorders, including many probiotics, live bacteria, as well as their derivatives and metabolic products, inacknowledgment of their major role. With significant developments in nanotechnology and biotechnology, the study and development ofmedication delivery systems based on these bacteria has grown rapidly in recent decades. Advances in genetic engineering methods haveenabled the insertion of plasmid vectors expressing proteins such as antigens, antibodies, cytokines, and enzymes into living bacteria.Attenuated pathogenic strains have demonstrated more diversified applicability among these genetically altered bacteria.

[学科分类] 药理学