ESKAPE Pathogens: Current Status and Emerging Challenges

[摘要] Needless to say, Anti-Microbial Resistance (AMR) is a global health concern in the present scenario threatening global progress in variousaspects which strikes hardest on the poor, cause untreatable infections even in the animals thereby affecting sustainable food production, andhealthcare systems and being an integral part of the environment, contaminating water and land with residues and many more. The causativemicrobes of this emerging resistance which has moved to the top 10 threats to public health as per WHO, include bacteria, fungi, viruses andparasites, of which bacteria have been observed to play a key role (WHO). The spread of this antimicrobial resistance can be attributed to avariety of factors including misuse and/or overuse of drugs leading to the spread via human contact, animal contact including food or viaenvironmental sources, lack of access to clean Water, Sanitation or Hygiene (WASH) for humans and animals, poor infection control inhealth care facilities, lack of awareness and knowledge and many more Further investigations in this direction have led to identification oftop priority pathogens list of WHO were in ESKAPE (virulent and antibiotic resistant bacterial pathogens) holds critical importance.

[学科分类] 药理学