Non-Hodgkin’s Lymphoma of Spleen: A Rare Site of Primary Presentation

[摘要] Background: Isolated splenic involvement in non-Hodgkin’s lymphoma is a rare clinical entity and is termed as primary splenic lymphoma (PSL). In such cases, the disease is mostly confined to spleen and splenic hilar lymph nodes. It usually presents with dragging pain in left side of abdomen and huge splenomegaly is detected on investigations. Splenectomy is the main modality of treatment followed by chemotherapy with or without radiation. Case Report: We present a rare case of PSL treated successfully at our institution with splenectomy and chemotherapy. Conclusion: Primary splenic lymphoma is a rare splenic neoplasm. Immunohistochemistry markers are helpful in confirming the diagnosis. Splenectomy is both diagnostic and therapeutic in such cases.

[学科分类] 生理学

[关键词] Primary Splenic Lymphoma;Non-Hodgkin’s Lymphoma;Splenectomy;Splenic radiation;Diffuse Large B-cell Lymphoma.