Endodontic management of a Von Willebrand's disease patient: A case report with short review

[摘要] Von Willebrand's disease (VWD) is a lifelong bleeding disorder in which the blood does not clot well. Mutations in the VWD gene cause VWD. The von Willebrand factor as a blood-clotting protein is provided by the VWF gene and is essential for the formation of blood clots. People with inherited bleeding disorders present a particular risk with regard to dental treatment. It is that these patients are treated safely and appropriately to avoid unnecessary risk of bleeding but also to minimize the use of clotting factor concentrate in situations where alternative methods of treatment can be effective. The aim of this case report is to provide information on how to handle a patient with a probably diagnosis of VWD with symptomatic irreversible pulpitis and symptomatic apical periodontitis of mandibular left second molar #37. The endodontic therapy was performed together with nonsurgical initial cause-related therapy. Even though the patient was on medication, the bleeding was obviously during the treatment. During follow-up period, the endodontic therapy was successfully. The strategy used in this case was effective in the management of coagulopathy and allowed emergency care to be carried out without complications.

[学科分类] 材料科学（综合）

[关键词] Endodontic therapy;symptomatic apical periodontitis;symptomatic irreversible pulpitis;von Willebrand's disease