Anti-photoaging Constituents from Eurya emarginata Leaves

[摘要] Eurya emarginata is an evergreen tree growing in the southern regions of Korea including Jeju Island. In thisstudy, antioxidant and anti-photoaging effects were investigated with the extracts of E. emarginata leaves. As comparativestudies with the extract and five solvent fractions, the EtOAc fraction showed the most effective DPPH and ABTS+ radicalscavenging activities. The EtOAc fraction also inhibited matrix metalloproteinase-1 (MMP-1) production most effectively.Phytochemical study on the EtOAC fraction resulted in the isolation of three compounds; eutigoside C (1), eutigoside B (2)and quercitrin (3). Among the isolates (1-3), quercitrin (3) showed excellent antioxidant activities and inhibitory properties onMMP-1 production. Based on these results, it was suggested that extracts of E. emarginata leaves could be developed as natural anti-photoaging agents in cosmetic formulations.

[学科分类] 化学（综合）

[关键词] Eurya emarginata;Anti-oxidant;Anti-photoaging;Quercitrin