Congenital cytomegalovirus infection-related thrombocytopenia

[摘要] A neonate with respiratory distress and no petechial rash was admitted to the neonatal intensive care unit. The initial blood count revealed thrombocytopenia. Results from the peripheral blood culture and additional biochemical tests were negative. Due to persistent thrombocytopenia, investigations were conducted for congenital cytomegalovirus (cCMV) infection. Positive results for CMV-specific immunoglobulins G and M were found on two separate occasions. Elevated blood levels of CMV DNA (4,285 copies/mL) 5 days after birth and high urinary levels of CMV DNA (1.96 million copies/mL) within 2 weeks of birth were detected. A computed tomography scan of the head detected periventricular calcifications (Figure 1). Magnetic resonance imaging of the brain confirmed bilateral periventricular white matter disease and cystic abnormalities in the right lateral ventricle (Figure 2).

[学科分类] 农业科学（综合）