Systemic Photodynamic Therapy With Chlorine e6 as a Photosensitizer for the Treatment of Nodular BCC: A Case Report

[摘要] Introduction:  Photodynamic therapy (PDT) is an established therapeutic method for basal cell carcinoma (BCC). BCC is the most common human cancer and also convenient cancer to treat using PDT. This is our experienced case report about Systemic Photodynamic Therapy with Chlorine e6 as a Photosensitizer for BCC Treatment. Case Report: A 78-year-old man was diagnosed with a 4-year history of nodular BCC on the nose area. The patient had under control and treatment for hypertension and type 2 diabetes. Chlorine e6 was injected intravenously at a dose of 0.08 mg/kg in 500cc normal saline within 20 minutes. After 3 hours of injection, Laser irradiation was performed with the wavelength of 665 nm, a dose of 150 j/cm2, the irradiance of 150 mW/cm2. His nodular BCC has been completely cured after 1 session of PDT with chlorin e6 without any side effects. Conclusion: Systemic PDT with Chlorine e6 as a Photosensitizer has been safe and effective in the removal of BCC lesions due to the data achieved in a two-month follow-up.

[学科分类] 基础医学

[关键词] Basal Cell Carcinoma (BCC);Photodynamic therapy (PDT);Chlorine e6