Does photobiomodulation therapy improve the postoperative outcomes of tonsillectomy? A systematic review and meta-analysis

[摘要] Introduction: Postoperative management of patients undergoing tonsillectomy is challenging.Photobiomodulation therapy (PBMT) has emerged as a new tool providing therapeutic benefits.However, the contribution of PBMT to the postoperative outcomes of tonsillectomy is still undefined.This systematic review and meta-analysis evaluated the published literature addressing the effects ofPBMT on post-tonsillectomy.Methods: Searches in Scopus, PubMed/MEDLINE, Embase, Web of Science, Cochrane Library,and grey literature were carried out for the identification of randomised controlled trials reportedup to August/2021. The risk of bias with the Cochrane Collaboration tool and meta-analysis wasperformed. Outcomes were assessed with the Kaplan-Meier method and the log-rank test.Results: A total of 1183 articles were retrieved, of which only two were included for qualitativeand quantitative analysis. The wavelengths were 685 nm and 980 nm with energy density set at 4J/cm². The mandibular angle and the surgical wound were the sites of laser irradiation. Individualswho had not undergone PBMT after tonsillectomy were more likely to report pain and odynophagiain the first 24 hours after surgery than individuals who had undergone PBMT after tonsillectomy(P<0.001). Children who received PBMT after tonsillectomy were equally affected by pain andodynophagia in the first seven days after surgery compared to children who had not undergonePBMT after tonsillectomy (P>0.05). However, both studies found a significant association of PBMTwith reduced analgesic consumption.Conclusion: Although PBMT seems promising for the management of individuals undergoingtonsillectomy, a limited number of studies are available in the literature.

[学科分类] 基础医学

[关键词] Complementary therapies;Low-level light therapy;Photobiomodulation therapy;Systematic review;Tonsillectomy.