Camel Milk a-lactalbumin As A Potential Anticancer Molecule: A Bioinformatics Analysis.

[摘要] α-lactalbumin-Oleic acid complex derived from milk is well known to have anti-cancer properties inmany diverse mammalian species including humans, goats and cows. The objective of the current study is tosee if α-lactalbumin present in camel’s milk too can serve as a potential anti-cancer molecule in its complexform. A comparative evaluation of α-lactalbumin structure among four mammalian species, viz, Camelusferus,Bostaurus, Homo sapiens, and Capra hircus has been made between the nucleotide sequences and structuresof protein. Furthermore, the physico-chemical properties, amino acid composition, position of disulfide bridgeformation in these species has been compared. The outcome of the present study suggests the presence of ananti-cancer property in the α-lactalbumin of camel, as has been experimentally observed in the other threespecies.

[学科分类] 工程和技术（综合）

[关键词] Camel milk;Anti-cancer;HAMLET;XAMLET;α-Lactalbumin;protein model. Computational analysis;Protein;DNA;Physicochemical properties;amini acid