Serum CDT (Carbohydrate Deficient Transferrin) levels among Indian Adult Alcoholic males with Alcoholic liver disease spectrum- An Observational Case Control study.

[摘要] Alcoholic liver disease comprises of spectrum of manifestations ranging from asymptomaticFatty liver to symptomatic Hepatitis, progressing to severely symptomatic Cirrhosis. The Study wasaimed at estimating the serum CDT levels among patients with Alcoholic liver disease spectrum toestablish its association. An Observational type Case Control study, with 120 study participants aged from20-60 years includes [ 90 Cases attending General OPD [ 30 cases in each of the three category ofalcoholic liver disease spectrum (Category I: Alcoholic fatty liver, Category II : Alcoholic hepatitis,Category III : Alcoholic cirrhosis)] & 30 healthy age matched Controls of Tamil Nadu Government MultiSuper Speciality Hospital, Chennai-2, conducted during the period between March – June 2020. There wassignificant difference between four groups [controls and case groups] for serum CDT levels by one wayANOVA (F ratio = 1050.609) (p=0.0001) even after multiple comparison by Tukey’s test showedsignificant difference existed in each pairwise comparison (p<0.01). The measurement of serum CDTlevels is imperative for finding its association and in identifying the progression of the Alcoholic liverdisease patients and improving the Quality of their life.

[学科分类] 工程和技术（综合）

[关键词] Alcoholic liver disease;Carbohydrate Deficient Transferrin;Progression.