A Study To Assess The Correlation Of D Dimer Levels In Prediction Of The Need Of Renal Replacement Therapy In COVID Patients With Acute Kidney Injury.

[摘要] Coronavirus disease 2019 is predominantly a respiratory illness that can cause hypercoagulablestates with multisystem involvement. A single centre retrospective study was carried out in 37 patientswho were diagnosed as COVID 19 with AKI from January 2022 to march 2022. Baseline D dimer wasevaluated on hospital admission . Patients who were diagnosed with AKI on admission or during the stayin hospital were included in the study , In this study 37 COVID patients with AKI were analysed. Mean ageof subjects was 62.51+/-15.18 years. Majority were in the age group 61-70 years (24.3%). 78.4% weremales and 21.6% were females. Mean blood urea among subjects was 131.86+/-56.55(mmol/L), meanserum creatinine was 4.71+/-2.52(mg/dl). mean d dimer at admission was 3.701+/-4.48570(mg/L).70.3%of subjects had AKI at hospital admission and 29.7% developed AKI during hospital stay. Cause of AKI wasprerenal in 89.2%, renal 18.9%,and post renal in 8.1%. D dimer levels >3.05 had highest validity inpredicting the need for RRT with sensitivity 39.29%, specificity 100%, positive predictive value of 100%and negative predictive value of 34.6%. from this study it was concluded that d dimer has specificity of100%in predicting the need of RRT .

[学科分类] 工程和技术（综合）

[关键词] AKI;Acute Kidney Injury;RRT:Renal Replacement Therapy;COVID 19:Coronavirus Disease;D Dimer.