A Study Comparing Intra-Incisional And Intra-Peritoneal Bupivacaine Infiltration In Controlling Post Operative Pain Following Laparoscopic Cholecystectomy: A Single Tertiary Care Centre Experience.

[摘要] Postoperative pain is one of the most common adverse events after day surgery with most1 studies reporting the incidence of moderate-to-severe postoperative pain reaching 25–30%.Laparoscopic cholecystectomy is one of the most frequently performed minimally invasive surgicalprocedures. To compare the efficacy of intra-incisional and intra-peritoneal infiltration bupivacaine onpostoperative pain relief in laparoscopic cholecystectomy. A sample of 150 patients undergoinglaparoscopic cholecystectomy were selected using simple random sampling technique. The patients wererandomly assigned into three groups 1, 2 and 3. Group 1 was the control group who did not receivebupivacaine either intra peritoneally or intra-incisionally. Group 2 patients received intra-peritonealinfiltration of 20 ml solution of 0.25% bupivacaine and intra-incisionalinfiltration of 20 ml solution of0.25% bupivacaine was given in Group 3. The study showed that Group 2 patients had better pain control as compared to group 3 patients. The VAS score at 30 minutes, 2 hours,4 hours ,12 hours and 24hours was statistically significant in group 2 when compared with the group 1 (control group) and significanttill 12hours when compared with group 3. The incidence of shoulder pain was higher in group 3 ascompared to group 2. The demand for rescue analgesia was also higher (54%) in group 3 compared togroup 2(44%). Intra-peritoneal infiltration of Bupivacaine provides better postoperative pain controlfollowing laparoscopic cholecystectomy and is associated with less requirement of analgesia in thepostoperative period.

[学科分类] 工程和技术（综合）

[关键词] intra-peritoneal bupivacaine infiltration;laparoscopic cholecystectomy.