Study Of Adverse Reactions In Whole Blood And Apheresis Donors At Tertiary Care Hospital.

[摘要] Blood and apheresis donations are widely considered to be safe with a low incidence of adversereactions and injuries but sometimes adverse reactions of varying severity may occur during or after thecompletion of blood donation process. This was a prospective study conducted on all allogenic wholeblood and apheresis donors over a period of one year at GGS Medical College & Hospital, Faridkot . Donorselection criteria were in accordance with Drug and cosmetic Act of India. Overall adverse reaction ratewas 0.3% i.e. 34 adverse reactions were reported in 13299allogenic whole blood donors and 3.8% i.e. 5in 133 apheresis donors. Vasovagal reactions were found to be the most common of all the donorreactions i.e.69.2%. Whereas citrate toxicity of mild type was among the most common adverse eventnoticed in cases of apheresis donors ie. 3.8%. Majority (56.4%) of adverse reaction were seen in youngerage group i.e. 18-30years. Citrate toxicity is the main cause for adverse reactions in apheresis. This can becorrected by continuous observation at the time of apheresis. If donor develop any of symptom of citratetoxicity i.e. numbness, tingling sensation, cardiac arrhythmia etc , calcium tablets or infusion should begiven during the procedure.

[学科分类] 工程和技术（综合）

[关键词] Citrate toxicity;adverse reactions;whole blood