A Study To Assess The Correlation Of Serum HDL As A Prognostic Marker In Sepsis.

[摘要] Sepsis is defined as life threatening organ dysfunction caused by a dysregulated host response toinfection. This study assessed use of serum HDL cholesterol as a prognostic indicator in sepsis andcompared its levels with APACHE 2 score for predicting mortality in sepsis patients. 50Patients admittedat KIMS Hospital, Bengaluru were included and followed up.. Serum HDL levels was evaluated on the dayof admission and repeated on day 5. APACHE 2 score was calculated for all patients on day of admission toestimate the risk of death. Most common causes of sepsis were MODS (64%) and acute lung injury (64%).Gram negative organism (26%) were most common among the positive blood cultured subjects comparedto the gram positive organisms (2%). Mean APACHE II score among the participants was 14.66. The meanserum HDL at the time of admission was 27.78 mg/dl and on 5th day of admission was 33.97mg/dl. SerumHDL levels on day 1 were higher in survivor group than non-survivor group. HDL levels increased insurvivor group compared to non-survivor groups on day 5. Serum HDL on admission at the cut off value of24mg/dl is apredictor of mortality among sepsis patients .

[学科分类] 工程和技术（综合）

[关键词] MODS: MULTI ORGAN DYSFUNCTION SYNDROME;Serum HDL;APACHE II.