Preparation, and Evaluation of physical properties of Schiff base- ß-Cyclodextrin inclusion Complexes

[摘要] Schiff base was prepared from the condensation of Sulfamethazine and N,N-dimethyl-4- aminobenzaldehyde, inclusion complexe was formed using β -cyclodextrin to encapsulate it. The mode ofinteraction and characterization were studies using IR, HNMR and SEM. Aqueous solubility was studythrough Higuchi and Connors method and the result show the improvement of solubility. by 3.5folds andthe complexes was formed in 1:1 molar ratio, the morphology of the particles was compared betweenSchiff base and their inclusion complexe and the result show the change in the surface, shape, and size.

[学科分类] 工程和技术（综合）

[关键词] Schiff base;cyclodestrin;complexes.