A Cross-Sectional Study On Electrocardiographic Changes In Chronic Kidney Disease Patients In A Tertiary Care Hospital, Bangalore, Karnataka, India.

[摘要] People with CKD are five to ten times more likely to die prematurely than they are to progress toend stage kidney disease. Cardiovascular disease is a major cause of mortality and morbidity amongpatients with CKD. More than 50 percent of patients with CKD die due to cardiovascular complications. Inaddition to the traditional risk factors such as coronary disease, diabetes, and left ventricular hypertrophy,patients with ESRD have an increased risk of mortality due to electrolyte disturbances, acid-base balance,and plasma volume shifts that occur during haemodialysis. The objective of present study is to study theElectrocardiographic changes in patients with Chronic Kidney Disease. In this study, 70 patients with CKDwere included to study the Electrocardiographic changes in patients with Chronic Kidney Disease. 47% ofthe study participants belonged to the age group between 51-60 years of age. The mean age of the studyparticipants was found to be 54.11+8.46 years. Majority of the study participants had diabetes (86%) andhypertension (61%). 64%) of the study participants had stage 3 CKD. 23% of the study participants hadLeft Ventricular Hypertrophy with 16% of study participants having ischemic changes in ECG. When ECGchanges were associated with Stages of CKD, association was found to be statistically significant betweenLeft Ventricular Hypertrophy as well as ischemic changes in CKD patients and Stages of CKD of the studyparticipants. Echocardiography provides a simple, non-invasive investigation that can identify evenasymptomatic patients at an earlier stage of CKD. So, earlier screening of CKD patients is recommended.The changes in ECG of patients with CKD can aid in detection of CVD and should be carried out in all patientswith CKD which may positively impact the care of the CKD population by permitting improved targeting ofcardiovascular risk reduction strategies. ECG abnormalities reflect the electrophysiological health of themyocardium and may reflect a combination of deregulations in ionic currents, metabolic changes,alterations in serum electrolytes, and secondary effects of medications. Future studies are recommendedto add additional cardiac work-up such as stress testing or cardiac/coronary computed tomographyscanning to ECG.

[学科分类] 工程和技术（综合）

[关键词] ECG changes;chronic kidney disease;cardiovascular disease;LVH.