Small fiber neuropathy in a patient with coronavirusdisease 2019 (COVID-19)

[摘要] Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel beta-coronavirus that causesa variety of symptoms in patients known as coronavirus disease (COVID-19). COVID-19 infectionmay cause complications involving the central nervous system (CNS), peripheral nervous system(PNS), muscles, or autonomic system (ANS). Compared with central and peripheral nervous systeminvolvement in COVID-19 infection reports, the bibliography describing ANS manifestations is morelimited. We report a patient with confirmed SARS-CoV-2, admitted to one of the tertiary hospitalsin Singapore with small fiber neuropathy. Small fiber neuropathy as a neurological manifestation inCOVID-19 infection is rare. Our case report adds to and supports this observation and also highlightshow SFN in COVID-19 infection can be self-limited without requiring immunosuppressive treatment.

[学科分类] 精神健康和精神病学

[关键词] COVID-19;Neurological complications;sudomotor dysautonomia;small fiber neuropathy;Sympathetic skin response