Atraumatic splenic rupture in acute myeloid leukemia

[摘要] A 50-year-old man with acute myeloid leukemia(AML) with a complex karyotype was admittedto the hospital with several days of dull, left-sided abdominal pain. His most recent bone marrow biopsyshowed 30% blasts, and immunophenotyping was suggestive of persistent AML (CD13+, CD34+, CD117+,CD33+, CD7+, MPO–). He was on treatment withvenetoclax and cytarabine after induction therapy hadfailed. On admission, his heart rate was 101 beats perminute and his blood pressure was 122/85 mm Hg.Abdominal examination revealed mild distention,hepatomegaly, and previously known massive splenomegaly, with the splenic tip extending to the umbilicus, and mild tenderness.

[学科分类] 卫生学