Beyond depression: Other uses for tricyclic antidepressants

[摘要] Tricyclic antidepressants (TCAs) were originally designedand marketed for treating depression, but over time theyhave been applied to a variety of conditions, mostly offlabel. TCAs can serve as first-line or augmenting drugsfor neuropathic pain, headache, migraine, gastrointestinal syndromes, fibromyalgia, pelvic pain, insomnia, andpsychiatric conditions other than depression. This articlereviews pharmacology, dosing, and safety considerationsfor these uses.

[学科分类] 卫生学