Neurofibromatosis-related phaeochromocytoma: two cases with large tumours and elevated plasma methoxytyramine
[摘要] We present two cases of adrenal phaeochromocytoma in patients with a previous diagnosis of neurofibromatosis type 1(NF1). One had an adrenergic phenotype. The other had a more noradrenergic phenotype. Both had large primarytumours, which increases the likelihood of malignancy. Both also had elevated plasma-free methoxytyramine, whichhas been linked with malignancy even in non-SDHB phaeochromocytomas.
[发布日期] [发布机构]
[效力级别] [学科分类] 血液学
[关键词] Adult;Female;Male;White;Australia;Adrenal;Tumours and neoplasia;Phaeochromocytoma;Neurofibromatosis;Takotsubo cardiomyopathy;Ischaemic heart disease;Cardiomyopathy;Headache;Palpitations;Dizziness;Sweating;Weight loss;Chest pain;Tachycardia;Neurofibromas;Abdominal lump;Hypertension;Electrocardiogram;Ultrasound scan;CT scan;Troponin;Liver function;Catecholamines (plasma);Metanephrines (plasma);Methoxytyramine;MIBG scan;Dopamine;MRI;Echocardiogram;Histopathology;Diltiazem;Digoxin;Prazosin;Alpha-blockers;Beta-blockers;Labetalol;Phenoxybenzamine;Metoprolol;Cardiology;Surgery;Unique/unexpected symptoms or presentations of a disease;August;2015 [时效性]
