Periconception and Prenatal Exposure to Maternal Perceived Stress and Cord Blood DNA Methylation

[摘要] Background: Maternal prenatal stress is associated with physiologic and adverse mental health outcomes in the offspring, but the underlying biologic mechanisms are unknown. We examined the associations of maternal perceived stress, including preconception exposure, with DNA methylation (DNAm) alterations in the cord blood buffy coats of 358 singleton infants.

[学科分类] 兽医学

[关键词] DNA methylation;epidemiology;perceived stress;periconception